In Japanese hospitals, there is a class of medication that is used very frequently, yet many people don’t truly understand it—
It is not a painkiller
Not a blood pressure medication
And not a “health supplement”
? It is an anticoagulant
Today, we’re talking about:
Rivaroxaban (brand name: Xarelto)

After visiting a hospital in Japan, many people are prescribed a medication:
? Xarelto (Rivaroxaban)
However, most simply “take it as directed” without really understanding:
✔ Why it’s taken this way
✔ Why the dosage varies
✔ What warning signs to watch for
Today, we’ll break down the instructions clearly ?
———
What is it used for?
Xarelto is mainly used to:
✔ Prevent stroke (ischemic stroke)
✔ Prevent systemic blood clots
✔ Treat deep vein thrombosis (DVT)
✔ Treat pulmonary embolism (PE)
✔ Prevent recurrence of blood clots
Especially for:
? Patients with non-valvular atrial fibrillation (key group)
In one sentence:
? This is a life-saving drug used to prevent blood clots
———
Dosage and usage (where most people get confused)
Different conditions require completely different dosing?
① Atrial fibrillation (stroke prevention)
? Standard:
15 mg × once daily (after meals)
? With impaired kidney function:
May be reduced to 10 mg per day
———
② Deep vein thrombosis / pulmonary embolism (initial phase)
? First 3 weeks:
15 mg × twice daily (after meals)
? Maintenance phase:
15 mg × once daily
———
Key point (often misunderstood):
? “Higher dose in the beginning” is NOT a mistake
? It’s to achieve rapid anticoagulation and prevent clot progression
———
Side effects (very important)
The main risk of this medication is:
? Bleeding
Common signs include:
Nosebleeds
Bleeding gums
Bruising under the skin
Blood in urine
Black stools (gastrointestinal bleeding)
Coughing up blood
Retinal bleeding
———
? Seek medical attention immediately if you notice:
? Black stools (very important)
? Unexplained or persistent bleeding
? Dizziness or fatigue (possible anemia)
? Go to the hospital right away
———
Who should be cautious?
The following groups must use it under strict medical supervision:
People with bleeding tendencies
History of gastric ulcers or gastrointestinal bleeding
Liver or kidney dysfunction
Those taking antiplatelet drugs (e.g., aspirin)
———
Three key points many people overlook
Must be taken after meals
→ Improves absorption
Do not stop the medication on your own
→ Risk of rebound clotting
Do not adjust the dose yourself
→ Extremely dangerous
———
? Xarelto is NOT a “supplement” or “wellness drug” — it is a risk-control medication
✔ Used correctly: prevents stroke and can save lives
❌ Used incorrectly: may lead to serious bleeding