Japan Original | Exelon® Rivastigmine Transdermal Patch For memory decline, Alzheimer’s disease, and other cognitive disorders
1/1/2026

As people grow older, gradual memory loss, slower reactions, and reduced judgment have become a reality many families have to face.

Cognitive impairment related to Alzheimer’s disease often develops quietly over time, yet it can affect almost every aspect of daily life without being immediately noticed.


In clinical practice, long-term and well-managed medication use is considered one of the important ways to slow disease progression and help maintain quality of life.


Today, we would like to introduce a prescription medication that has been widely used in Japan —

Exelon® Rivastigmine Transdermal Patch 4.5 mg.

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Rivastigmine (Exelon®) Transdermal Patch 4.5 mg “Sawai”

14 patches per box

Helps support memory function, reduce forgetfulness, and assist normal brain activity.

May help slow memory decline, improve cognitive performance, and ease symptoms associated with Alzheimer’s-related dementia, supporting clearer thinking, daily judgment, and responsiveness.


What conditions is it mainly used for?


Rivastigmine is commonly prescribed for mild to moderate Alzheimer’s-type dementia.

After evaluation by a physician, it is typically used in individuals experiencing gradual declines in memory, attention, and overall cognitive function.


With continuous and appropriate use, it helps support communication between brain cells and may, to a certain extent:


Slow further memory decline


Improve attention and responsiveness


Help maintain daily cognitive function


It is important to understand that this type of medication does not cure the disease. However, when used as directed, it may help slow symptom progression and keep the condition more stable over time.


Why choose a transdermal patch?


In real-world use, many patients and caregivers prefer the patch form for practical reasons.


Compared with oral medication, transdermal patches offer several advantages:


More stable medication release


Once-daily application, simple to use


Less irritation to the gastrointestinal system


Better suited for people with swallowing difficulties or poor medication adherence


By being absorbed gradually through the skin, the patch helps reduce fluctuations in drug levels and allows the body to adapt more smoothly.


Simple to use, but proper use is important


In most cases, treatment starts at 4.5 mg per day:


Replace the patch every 24 hours


Apply to intact skin on the back, upper arm, or chest


Rotate application sites daily to avoid repeated skin irritation


Any dose adjustments should be determined by a physician based on tolerance and changes in the patient’s condition.


Possible side effects


Most users tolerate the patch well. However, some individuals may experience:


Mild redness or itching at the application site


Reduced appetite or nausea


Mild dizziness or fatigue


If symptoms are noticeable or persist, medical advice should be sought. Do not stop or adjust the medication without consulting a healthcare professional.


Who may be considered for use?


After professional assessment, Rivastigmine transdermal patches may be considered for individuals who:


Show noticeable memory decline


Frequently forget things or ask the same questions repeatedly


Experience reduced judgment or executive function


Have been diagnosed with mild to moderate Alzheimer’s-type dementia


All medications for cognitive disorders should be used under medical supervision.


Product information


Product name: Exelon® Rivastigmine Transdermal Patch


Strength & pack size: 4.5 mg × 14 patches


Country of origin: Japan


Dosage form: Transdermal patch


Dosing frequency: Once daily


Final note


Changes in cognitive function do not happen overnight and should not be overlooked.

The earlier proper management begins, the greater the chance of slowing progression and maintaining quality of life for a longer period.


When facing cognitive impairment,

appropriate medication use, patient companionship, and ongoing communication

are often the most important and realistic forms of support for families.


This content is for health information purposes only and does not replace professional medical diagnosis or treatment advice.






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