Tsumura Hachimijiogan Granules is a classic Kampo (traditional Japanese) formulation, known for its highly concentrated ingredients and notable warming and tonifying effects. It provides an effective solution for patients experiencing symptoms such as fatigue, cold extremities, and kidney yang deficiency. This article provides a detailed overview of the formulation, including its ingredients, medicinal effects, usage, dosage, and precautions to help patients better understand and utilize this Kampo medicine.
Basic Information
Ingredients
Tsumura Hachimijiogan Granules contains the dried extracts of the following traditional Chinese medicinal herbs:
Rehmannia Root (Shu Di Huang): 6.0g
Cornus Fruit (Shan Zhu Yu): 3.0g
Dioscorea (Shan Yao): 3.0g
Alisma (Ze Xie): 3.0g
Poria (Fu Ling): 3.0g
Moutan Bark (Mu Dan Pi): 2.5g
Cinnamon Twig (Gui Zhi): 1.0g
Aconite Root (Fu Zi): 0.5g
Additional excipients include magnesium stearate, lactose, and sucrose fatty acid esters.
Product Specifications
Each package contains 2.5g x 42 sachets, sufficient for a 14-day supply.
Mechanism of Action
Warming and Tonifying Kidney Yang
Tsumura Hachimijiogan Granules primarily works by warming and strengthening kidney yang. The ingredients Aconite Root and Cinnamon Twig play a central role in warming the body, helping relieve symptoms such as cold limbs and lower back and knee weakness.
Nourishing Yin and Tonifying the Kidneys
Herbs such as Rehmannia, Dioscorea, and Cornus nourish kidney yin, helping to relieve symptoms like excessive thirst and frequent urination caused by yin deficiency.
Balancing Yin and Yang
By combining warming and nourishing effects, this formula helps balance the body’s yin and yang, improving overall vitality and strengthening the constitution.
Clinical Applications
Indications
Tsumura Hachimijiogan Granules is mainly used to treat the following symptoms and conditions:
Fatigue and cold extremities: Helps alleviate tiredness and cold limbs caused by kidney yang deficiency.
Lower back and knee weakness: Relieves soreness and weakness due to kidney deficiency.
Frequent urination or reduced urine output: Improves urination issues linked to kidney problems.
Excessive thirst: Addresses symptoms of thirst due to kidney yin deficiency.
Other related conditions: Can support treatment for nephritis, diabetes, erectile dysfunction, sciatica, and hypertension.
Dosage and Administration
Adults
The typical adult dosage is 7.5g per day, divided into 2 to 3 doses. It should be taken orally 2–3 hours before or after meals. Dosage can be adjusted according to age, body weight, and symptoms.
Children
Dosage for children should be adjusted based on age and weight, and it is recommended to be administered under medical supervision.
Safety and Precautions
Common Side Effects
Possible side effects when using Tsumura Hachimijiogan Granules include:
Skin rash, redness, itching
Loss of appetite, stomach discomfort
Nausea, vomiting
Abdominal pain, diarrhea, constipation
Fatigue, palpitations, hot flashes, numbness of the tongue
If any of these symptoms occur, consult a physician or pharmacist promptly.
Precautions
Use with caution in the following cases:
Robust individuals: More likely to experience side effects or worsening of symptoms.
People prone to heat or hot flashes: May experience palpitations, hot flashes, nausea, or tongue numbness.
Patients with weak digestion: May experience appetite loss, stomach upset, nausea, vomiting, diarrhea, or constipation.
Those already experiencing nausea or vomiting: Symptoms may be exacerbated.
General Cautions:
Consider the patient's overall constitution and symptoms before using the medicine.
Monitor symptoms carefully during use. If no improvement is seen, discontinue use.
When taking with other Kampo medicines, ensure there is no ingredient overlap—especially regarding Aconite Root, which requires special caution.
Contraindications
Refer to the product’s official instructions for specific contraindications.
Conclusion
Tsumura Hachimijiogan Granules is a powerful Kampo remedy that combines warming yang and nourishing yin actions to effectively relieve a variety of symptoms caused by kidney deficiency, such as fatigue, cold limbs, and lower back soreness. However, it is essential to use the medicine under proper guidance, paying close attention to possible side effects and contraindications. With correct usage, this Kampo preparation can provide strong support for individuals seeking to improve their vitality and overall health.