What is Vitiligo?

Vitiligo is a condition characterized by depigmented patches on the skin or mucous membranes. The exact cause of its onset is not yet fully understood. The disease presents as well-defined white patches that can appear locally or be widely distributed, affecting various parts of the body. Vitiligo not only significantly impacts the patient’s appearance but can also lead to considerable psychological stress.

Symptoms of Vitiligo

Clinical Manifestations

Shape of White Patches

In the early stages, the white patches of vitiligo are typically the size of a fingernail or a coin and are often round, oval, or irregular in shape. As the disease progresses, the patches gradually enlarge, and their boundaries may become less distinct, merging with adjacent patches to form irregular, map-like shapes.

Color of White Patches

Initially, the patches appear light white or milky white. With the progression of the disease, melanin in the affected areas diminishes or is entirely lost, causing the patches to develop into porcelain white with a more noticeable contrast to surrounding skin.

Commonly Affected Areas

Vitiligo frequently occurs on exposed or friction-prone areas, such as the face, neck, backs of the hands, wrists, and forearms. Mucosal areas such as the lips and genital mucosa may also be affected. In some cases, the scalp is involved, leading to localized whitening of hair.

Mechanisms of Vitiligo Onset

Autoimmune Factors

Vitiligo may be an autoimmune disease, wherein the immune system mistakenly identifies melanocytes as "enemies" and attacks them, leading to their damage or destruction. This results in impaired melanin synthesis.

Genetic Factors

Vitiligo has a certain hereditary tendency, with some patients having family members with similar conditions. Studies have shown that numerous genes are involved in vitiligo's development, encompassing multiple pathways. Its inheritance pattern is complex and cannot be explained by single-gene inheritance.

Neuropsychological Factors

Chronic psychological stress, excessive pressure, anxiety, and depression may interfere with the synthesis and secretion of neurotransmitters. These disruptions can further impair melanocyte function, accelerating the depigmentation process.

Melanocyte Self-Destruction Theory

During melanin synthesis, melanocytes produce intermediate byproducts that can be toxic. When these byproducts are not promptly cleared, they accumulate and directly damage melanocytes, eventually leading to their dysfunction.

Trace Element Deficiency

Trace elements such as copper and zinc are essential cofactors in melanin synthesis, particularly for maintaining tyrosinase activity. A deficiency in these elements reduces tyrosinase activity, thereby impairing normal melanin production.

Universal Purple Ointment: A Multi-Purpose Treatment for Vitiligo, Eczema, Dermatitis, and Psoriasis

Locoid (Hydrocortisone Butyrate 0.1%) Ointment: 5g × 10 Tubes

Product Introduction

Product Name

Torii Universal Purple Ointment

Country of Origin

Japan

Manufacturer

Torii Pharmaceutical Co., Ltd.

Specifications

5g per tube, 10 tubes per box

Product Efficacy

This Japanese prescription ointment, known as a "universal remedy," is a powerful skin inflammation suppressant with broad-spectrum indications. Its primary functions include improving various skin conditions such as:

Vitiligo: Reduces inflammatory reactions in depigmented areas and promotes skin recovery.

Psoriasis: Effectively alleviates symptoms such as scaling, itching, and redness.

Urticaria: Relieves localized itching and rashes.

Xerosis (Dry Skin): Moisturizes the skin, reducing cracking and peeling.

Melanosis: Improves skin issues caused by abnormal pigmentation.

Seborrheic Dermatitis: Soothes oily, red, and itchy areas on the scalp and face.

Eczema and Other Skin Issues: Provides relief for itchy rashes caused by irritation or allergies, diaper rash (in infants), wind-induced facial redness, infantile skin lichenification, and more.

Target Users

Suitable for all age groups, including adults and infants.

Recommended for patients experiencing skin inflammation, itching, dryness, flaking, and other related symptoms.

Usage Instructions

Application Frequency

Apply 3–4 times daily at evenly spaced intervals.

Application Method

Take an appropriate amount of the ointment and gently apply it to the affected area.

Avoid vigorous rubbing to prevent skin irritation.

Conditions for Use

Ensure the skin is clean and dry before applying the ointment to improve absorption.

For children, especially infants, use under the guidance of a doctor or caregiver, particularly on sensitive skin areas.

Precautions

This product is for external use only. Do not ingest, and avoid contact with eyes, mouth, or other mucous membranes.

Do not use if you are allergic to any of the ingredients.

If symptoms do not improve after prolonged use, consult a doctor promptly.

Store in a cool, dry place away from direct sunlight and out of reach of children.

Storage Conditions

Recommended storage temperature: Below 25°C.

Avoid humid environments to maintain the ointment’s stability and effectiveness.

Friendly Reminder

This is a prescription medication and is recommended for use under a doctor’s supervision. If applying to infants or sensitive skin areas, monitor for adverse reactions and avoid excessive application to prevent irritation or side effects.