“No More Worry About Hurting Your Liver or Kidneys While Lowering Uric Acid”
“A New Hope for Gout Patients from Japan”
When gout strikes, the pain is so intense — it feels like your soul is trembling! ?
Many people start taking uric acid–lowering drugs,
only to find their liver and kidney functions getting worse over time.
The thought of taking medicine long-term can be scary...
But here’s the good news ?
Japan’s new drug Dotinurad is quietly changing everything! ?
Recently Launched Worldwide — Not Yet Available in China!
This medication, developed by Fuji Pharma in Japan,
was launched as early as 2020 in Japan, North America, and Europe.
It has been recognized as “the latest generation of uric acid–lowering drugs” worldwide.
Although it has not yet been officially approved in China,
it has already attracted strong attention in the medical and pharmaceutical communities.
Many experts call it:
“A gentler and safer new option for uric acid control.”
How Does It Lower Uric Acid So Gently?
Most traditional uric acid–lowering drugs work by suppressing uric acid production,
but that often puts extra strain on the liver and kidneys.
Dotinurad takes a completely different approach
It works by inhibiting the URAT1 and OAT4 transporters in the renal tubules,
which helps reduce uric acid reabsorption and increase uric acid excretion.
Simply put:
Prevents uric acid “backflow”
Helps the body eliminate excess uric acid
Lowers uric acid concentration in the blood
Reduces gout flare-ups
The result?
More safety, longer-lasting effect, and minimal impact on the liver and kidneys!
What Do Clinical Studies Show?
Multiple Phase III clinical trials have demonstrated that:
The rate of liver function abnormalities with Dotinurad is significantly lower
Uric acid reduction is more stable and consistent than with Febuxostat
It is safer for long-term use
Doctors have widely described it as:
“A safer uric acid–lowering option, especially for patients requiring long-term control.”
Dosage Information (For Reference Only)
Always follow your doctor’s instructions. Do not self-medicate.
Period Dosage Frequency
Weeks 1–2 0.5 mg Once daily
Weeks 3–5 1 mg Once daily
After Week 6 2 mg Once daily (maintenance phase)
The goal is to maintain serum uric acid around 300 μmol/L,
which helps prevent gout attacks without burdening the liver or kidneys.
Why Are More Doctors Recommending It?
Minimal impact on liver and kidney function
More thorough and stable uric acid reduction
Safe for long-term use
Noticeably fewer gout flare-ups
In short:
“Better control, lighter body!”
Tips for Patients
Dotinurad is not yet available in China.
If you’re considering it, consult a qualified doctor or medical institution.
Avoid buying unverified “imported” or “gray market” drugs — they carry high risk.
Medication is only part of gout management.
Healthy habits like a low-purine diet, drinking enough water, and regular checkups are just as important!
Final Thoughts
Health is a marathon, not a sprint.
Stay patient, stay scientific,
and let every gout patient enjoy life — without pain.
Recommended Tags
#gouttreatment #Dotinurad #uricacidcontrol #liverkidneyprotection
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Do you know someone suffering from gout?
Share this article with them —
so more people can learn about this safer and smarter way to control uric acid!