Feburic Febuxostat Tablets 10mg – Teijin Japan | Gout & Hyperuricemia Treatment | 100 Tablets

■ Product Name:

Febuxostat

■ Active Ingredient:

Febuxostat

■ Dosage Form & Appearance:

White to slightly yellowish film-coated tablets, approx. 7mm in diameter

■ Package Markings:

フェブリク (Feburic) 10mg / 20mg / 40mg

? Indications & Effects

Febuxostat is a prescription medication used to treat gout and hyperuricemia (high uric acid levels).

It works by inhibiting the enzyme xanthine oxidase, which reduces uric acid production in the body, thereby helping to prevent gout attacks and related complications.

? Dosage & Administration

Initial Dose:

Usually starts at 10mg once daily, with or without food.

Dose Adjustment:

Based on blood uric acid levels, the dose may be increased to 20mg once daily after 3–6 weeks. After 7 weeks, the maintenance dose may be increased to 40mg per day.

Maximum Dose:

Should not exceed 60mg per day. Dosage must be determined by a physician.

Missed Dose Instructions:

If a dose is missed, take it as soon as possible.

If it's close to the next scheduled dose, skip the missed one.

Do not double the dose to make up for a missed dose.

⚠️ Precautions

Inform your doctor or pharmacist if you:

Have had allergic reactions to medications (e.g., rash, itching);

Are pregnant or breastfeeding;

Are currently taking other medications, including over-the-counter drugs or health supplements.

Febuxostat may interact with other drugs and either enhance or reduce its effects.

❗ Common Side Effects

May include:

Gouty arthritis

Joint pain

Discomfort or pain in limbs

Diarrhea

Fatigue

Stop taking the medication and consult your doctor if you experience:

Extreme fatigue, appetite loss, yellowing of the skin or eyes → Possible liver dysfunction

Widespread rash or severe itching → Possible allergic reaction

※ These are not all possible side effects. If you notice any unusual symptoms, seek medical advice immediately.

? Precautions During Treatment

1️⃣ Regular Monitoring of Uric Acid and Liver Function

Monitor uric acid levels regularly, especially during dose changes.

Febuxostat may affect liver function; regular liver function tests (e.g., AST, ALT) are recommended.

2️⃣ Risk of Initial Gout Flare ("Rebound Effect")

Uric acid fluctuations in early treatment may temporarily trigger gout attacks.

Do not stop or increase the dosage on your own. Doctors may prescribe preventative medications like colchicine or NSAIDs.

3️⃣ Do Not Adjust or Stop Medication Without Doctor's Advice

Febuxostat requires consistent and long-term use to control uric acid levels.

If a dose is missed, never double the dose. Always consult your doctor before making changes.

4️⃣ Diet and Alcohol Considerations

Even with medication, dietary management is important:

Avoid organ meats, seafood, rich broths, and other high-purine foods;

Limit alcohol, especially beer and spirits, as they raise uric acid levels.

5️⃣ Drug Interactions

Use with caution when combining with:

Immunosuppressants (e.g., azathioprine, 6-mercaptopurine);

Cardiovascular medications;

Anticoagulants (e.g., warfarin).

Before starting any new medication or supplement, consult your doctor or pharmacist.

6️⃣ Seek Medical Help for Serious Symptoms

Discontinue use and seek medical attention if you experience:

Yellowing of the skin or eyes, suggesting liver dysfunction;

Fatigue, appetite loss;

Skin rash, difficulty breathing, or throat swelling, indicating a possible allergic reaction.